Services

I provide comprehensive surgical, anesthetic, and image‑guided procedural support across multispecies preclinical models. My work spans major and minor survival and non‑survival procedures, complex interventional therapies, advanced anesthetic management, and full‑spectrum monitoring and critical support — delivered on‑site at your facility for surgical and anesthetic work, and aligned with GLP, IACUC, USDA, and AAALAC standards throughout. NiKara Preclinical works nationwide with CROs, academic institutions, biotech companies, and medical device programs.

My services are built around real procedural experience, not theory. As your contracted specialist, I integrate directly into your workflow to support the models, devices, and timelines that matter most in active study environments.

Specialized Support for Preclinical Research

Large and Small Animal, GLP/Non-GLP

  • Surgical Model & Device Implantation

    Major and minor survival and non‑survival surgical models (GLP and non‑GLP), inductive disease modeling, and implant models including device placement, revision, explant, and vascular access creation and maintenance.

  • Endovascular & Image‑Guided Interventions

    Percutaneous and transcatheter vascular interventions, endovascular device deployment and retrieval, and image‑guided procedural models in catheterization lab and hybrid OR environments.

  • General & Translational Surgery

    Hemostasis and hemorrhage control models, GI surgical models, cardiothoracic procedures, wound healing and tissue repair models, and microsurgical models including vascular anastomosis and nerve repair.

  • Orthopedic, Oncology & Craniofacial

    Oncology models including tumor induction and image‑guided FNA; dental and craniofacial procedures; and orthopedic models including critical‑sized bone defects and osteotomy procedures.

  • Neuromodulation & Implantable Devices

    Telemetry device placement, peripheral nerve and tendon grafting, implantable pulse generator placement and programming, and central/peripheral nerve stimulation device implantation.

  • Anesthesia, Analgesia & Physiologic Support

    Multispecies anesthetic management for survival and terminal procedures, TIVA/PIVA and CRI/TCI‑based protocols, and comprehensive multimodal pain management across all procedural phases.

  • Monitoring, Access & Critical Support

    Advanced hemodynamic and respiratory monitoring, arterial and venous catheter placement, blood gas sampling, and arrhythmia recognition and procedural management.

  • Training, Replication & Technical Validation

    Procedure replication and skills validation for internal teams and sponsors, wet lab, dry lab, and simulation‑based training aligned with GLP, IACUC, USDA, and AAALAC standards.

  • Necropsy & Post‑Procedural Evaluation

    Gross necropsy and tissue collection for studies not requiring a DVM pathologist, and device and procedural outcome assessment to support study endpoints.

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Full-Spectrum Study Direction, Now Part of NiKara Preclinical

NiKara Preclinical now offers complete study direction support — protocol development, study design consultation, IACUC submission support, data review, and regulatory report writing — alongside hands-on surgical and anesthetic execution.

This expanded capability is delivered through NiKara Preclinical's network of seasoned, independent Study Directors with deep multispecies and multimodal experience — available both to sponsors seeking direct, flexible support and to CROs and institutions needing contract study director capacity for overflow studies.

Ask About Study Director Support